Crystal structure of spleen tyrosine kinase complexed with 2-(6-Chloro-1-methyl-1H-indazol-3-yl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid isopropylamide

PDB Details

PDB ID
4I0S
Status
CURRENT
Deposition Date
2012-11-19
Modification Date
2013-10-30
Pubmed ID
23350847
Method
X-RAY DIFFRACTION
Resolution (Å)
1.98
UniProt Accessions
P43405

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 4 9
A C EDI 5 9
A N ATP 1 17
A N DFG 3 12
A N ATP 4 9
A N MPP 7 4
A N ATP 8 2

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Legend

Color Name Hit Count