Crystal structure of spleen tyrosine kinase complexed with 2-(5,6,7,8-Tetrahydro-imidazo[1,5-a]pyridin-1-yl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid tert-butylamide

PDB Details

PDB ID
4I0T
Status
CURRENT
Deposition Date
2012-11-19
Modification Date
2013-10-30
Pubmed ID
23350847
Method
X-RAY DIFFRACTION
Resolution (Å)
1.7
UniProt Accessions
P43405

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 4 11
A C PDIG 6 6
A N ATP 1 15
A N MPP 2 12
A N ATP 6 4
A N ATP 7 3
A N MPP 8 2
A N DFG 9 2

Mapping Results Viewer

Use your mouse to drag, rotate, and zoom. Select structure to view on the right using dropdown.

Legend

Color Name Hit Count