Crystal structure of the monomeric (V948R) form of the gefitinib/erlotinib resistant EGFR kinase domain L858R+T790M

PDB Details

PDB ID
4I1Z
Status
CURRENT
Deposition Date
2012-11-21
Modification Date
2013-02-27
Pubmed ID
23273428
Method
X-RAY DIFFRACTION
Resolution (Å)
3.0
UniProt Accessions
P00533

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DRS 3 8
A C CMP 6 6
A C PDIG 11 2
A N MPP 0 19
A N MT3 1 18
A N MT3 3 13
A N ATP 5 11
A N MT3 6 2

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Legend

Color Name Hit Count