Crystal structure of L858R + T790M EGFR kinase domain in complex with MIG6 peptide

PDB Details

PDB ID
4I21
Status
CURRENT
Deposition Date
2012-11-21
Modification Date
2013-02-27
Pubmed ID
23273428
Method
X-RAY DIFFRACTION
Resolution (Å)
3.37
UniProt Accessions
P00533

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C LBP 4 8
A C ATP 6 5
A C EDI 9 2
A C DFG 10 2
A N MT3 0 15
A N MT3 1 15
A N MPP 4 8
A N ATP 5 7
A N PIF 6 5
A N MPP 8 4
B C ATP 7 3
B C DRS 9 2
B N MT3 0 17
B N MT3 3 9
B N MT3 4 8
B N MPP 5 8
B N ATP 6 6
B N PIF 7 4

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Legend

Color Name Hit Count