Crystal Structure of Human PRPF4B kinase domain in complex with 4-{5-[(2-Chloro-pyridin-4-ylmethyl)-carbamoyl]-thiophen-2-yl}-benzo[b]thiophene-2-carboxylic acid amine

PDB Details

PDB ID
4IJP
Status
CURRENT
Deposition Date
2012-12-22
Modification Date
2013-11-06
Pubmed ID
24003220
Method
X-RAY DIFFRACTION
Resolution (Å)
2.25
UniProt Accessions
Q13523

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 1 20
A C CMP 2 19
A C EDI 3 18
A N MPP 1 18
A N ATP 2 13
A N ATP 3 12
A N DFG 6 2
A N DFG 9 2
A N ATP 10 2
B C PDIG 0 22
B C CMP 2 18
B C EDI 3 16
B N MPP 0 16
B N ATP 1 16
B N DFG 4 9
B N ATP 7 4
B N DFG 9 2

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Legend

Color Name Hit Count