Q13523

Background

Protein Name
Serine/threonine-protein kinase PRP4 homolog
Gene Name
PRPF4B
Organism
Homo sapiens

Annotations

Function
Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.

Mapping Statistics

Site Maximum Consensus Site Population Minimum Consensus Site Population Median Consensus Site Population
MPP 18 16 16.0
DFG 13 2 8.0
EDI 18 10 14.5
MT3 19 9 16.0
CMP 22 3 12.0
PDIG 22 13 17.5
ATP 16 2 10.0

Mapping Results

PDB ID Maximum Consensus Site Population
MPP site DFG site PIF site DRS site DEF site EDI site MT3 site AAS site LBP site CMP site PDIG site ATP site PMP site
Total Druggable Structures per Site 4 0 0 0 0 2 2 0 0 3 3 1 0
4IFC 16 9 0 0 0 15 19 0 0 22 19 10 0
4IIR 16 12 0 0 0 17 18 0 0 14 15 10 0
4IAN 18 13 0 0 0 14 0 0 0 18 18 14 0
4IJP 18 9 0 0 0 18 0 0 0 19 22 16 0