ITK kinase domain in complex with benzothiazole inhibitor 12b (1S,2S)-2-{4-[(DIMETHYLAMINO)METHYL]PHENYL}-N-[6-(1H-PYRAZOL-4-YL)-1,3-BENZOTHIAZOL-2-YL]CYCLOPROPANECARBOXAMIDE

PDB Details

PDB ID
4MF1
Status
CURRENT
Deposition Date
2013-08-27
Modification Date
2013-11-20
Pubmed ID
24138940
Method
X-RAY DIFFRACTION
Resolution (Å)
2.11
UniProt Accessions
Q08881

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DRS 1 16
A C AAS 4 13
A C CMP 5 8
A N ATP 1 15
A N ATP 3 12
A N ATP 4 10
A N MPP 8 2

Mapping Results Viewer

Use your mouse to drag, rotate, and zoom. Select structure to view on the right using dropdown.
Powered by NGL

Legend

Color Name Hit Count