The crystal structure of DYRK1a with a bound pyrido[2,3-d]pyrimidine inhibitor

PDB Details

PDB ID
4MQ2
Status
CURRENT
Deposition Date
2013-09-15
Modification Date
2013-12-18
Pubmed ID
24239188
Method
X-RAY DIFFRACTION
Resolution (Å)
2.8
UniProt Accessions
Q13627

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 0 17
A C DRS 3 12
A C PDIG 5 8
A C EDI 8 3
A N PIF 0 24
A N ATP 1 20
A N ATP 6 6
A N ATP 8 2
A N DFG 9 1

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Legend

Color Name Hit Count