Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitor

PDB Details

PDB ID
4R1Y
Status
CURRENT
Deposition Date
2014-08-08
Modification Date
2015-04-22
Pubmed ID
25736998
Method
X-RAY DIFFRACTION
Resolution (Å)
2.0
UniProt Accessions
P08581

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 1 14
A C DRS 6 7
A C DRS 8 5
A C ATP 11 4
A N ATP 2 16
A N MT3 3 15
A N MT3 4 14
A N PIF 5 7
A N MPP 6 6
A N MT3 7 4

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Legend

Color Name Hit Count