ITK kinase domain in complex with compound 1 N-{1-[(1,1-dioxo-1-thian-2-yl)(phenyl)methyl]-1H- pyrazol-4-yl}-5,5-difluoro-5a-methyl-1H,4H,4aH,5H,5aH,6H-cyclopropa[f]indazole-3-carboxamide

PDB Details

PDB ID
4RFM
Status
CURRENT
Deposition Date
2014-09-26
Modification Date
2015-08-26
Pubmed ID
25844760
Method
X-RAY DIFFRACTION
Resolution (Å)
2.1
UniProt Accessions
Q08881

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C AAS 2 12
A C DRS 7 6
A C AAS 9 2
A N ATP 0 24
A N MT3 1 19
A N MT3 2 16
A N ATP 3 15
A N ATP 5 6
A N PIF 6 4

Mapping Results Viewer

Use your mouse to drag, rotate, and zoom. Select structure to view on the right using dropdown.
Powered by NGL

Legend

Color Name Hit Count