Crystal structure of V561M FGFR1 gatekeeper mutation (C488A, C584S, V561M) in complex with N-{3-[2-(3,5-DIMETHOXYPHENYL)ETHYL]-1H-PYRAZOL-5-YL}-4-[(3R,5S)-3,5-DIMETHYLPIPERAZIN-1-YL]BENZAMIDE (AZD4547)

PDB Details

PDB ID
4RWK
Status
CURRENT
Deposition Date
2014-12-04
Modification Date
2015-05-27
Pubmed ID
25686244
Method
X-RAY DIFFRACTION
Resolution (Å)
2.98
UniProt Accessions
P11362

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A N MPP 1 15
A N ATP 2 13
A N MPP 5 8

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Legend

Color Name Hit Count