Co-crystal Structure of PERK bound to 4-{2-amino-3-[5-fluoro-2-(methylamino)quinazolin-6-yl]-4-methylbenzoyl}-1-methyl-2,5-diphenyl-1,2-dihydro-3H-pyrazol-3-one inhibitor

PDB Details

PDB ID
4X7K
Status
CURRENT
Deposition Date
2014-12-09
Modification Date
2015-02-25
Pubmed ID
25587754
Method
X-RAY DIFFRACTION
Resolution (Å)
1.8
UniProt Accessions
Q9NZJ5

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DRS 3 10
A C DFG 4 9
A C AAS 7 5
A C DFG 8 4
A C ATP 10 2
A N MT3 1 19
A N MT3 2 14

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Legend

Color Name Hit Count