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Co-crystal Structure of PERK bound to 4-{2-amino-4-methyl-3-[2-(methylamino)-1,3-benzothiazol-6-yl]benzoyl}-1-methyl-2,5-diphenyl-1,2-dihydro-3H-pyrazol-3-one inhibitor
PDB Details
PDB ID
4X7L
Status
CURRENT
Deposition Date
2014-12-09
Modification Date
2015-02-25
Pubmed ID
25587754
Method
X-RAY DIFFRACTION
Resolution (Å)
1.9
UniProt Accessions
Q9NZJ5
Mapping Results
Chain
Terminus
Site
Consensus Site Rank
Consensus Site Population
A
C
DRS
3
9
A
C
DFG
5
6
A
C
ATP
7
4
A
C
DRS
8
2
A
N
ATP
1
21
A
N
MT3
2
17
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Chain: A
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Name
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Chain: A