Co-crystal Structure of PERK bound to 4-[2-amino-4-methyl-3-(2-methylquinolin-6-yl)benzoyl]-1-methyl-2,5-diphenyl-1,2-dihydro-3H-pyrazol-3-one inhibitor

PDB Details

PDB ID
4X7N
Status
CURRENT
Deposition Date
2014-12-09
Modification Date
2015-02-25
Pubmed ID
25587754
Method
X-RAY DIFFRACTION
Resolution (Å)
2.35
UniProt Accessions
Q9NZJ5

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DFG 4 8
A C DRS 5 8
A C AAS 6 5
A C ATP 8 3
A N MT3 1 16
A N ATP 2 15
A N MT3 6 6

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Legend

Color Name Hit Count