Co-crystal Structure of PERK bound to 1-[5-(4-amino-2,7-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1H-indol-1-yl]-2-[3-fluoro-5-(trifluoromethyl)phenyl]ethanone inhibitor

PDB Details

PDB ID
4X7O
Status
CURRENT
Deposition Date
2014-12-09
Modification Date
2015-02-25
Pubmed ID
25587754
Method
X-RAY DIFFRACTION
Resolution (Å)
2.65
UniProt Accessions
Q9NZJ5

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 1 14
A C DRS 3 11
A C AAS 8 6
A C DRS 9 3
A N MT3 0 20
A N ATP 3 13
A N MT3 4 12

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Legend

Color Name Hit Count