Crystal structure of the FLT3 kinase domain bound to the inhibitor quizartinib (AC220)

PDB Details

PDB ID
4XUF
Status
CURRENT
Deposition Date
2015-01-25
Modification Date
2015-08-26
Pubmed ID
25837374
Method
X-RAY DIFFRACTION
Resolution (Å)
3.2
UniProt Accessions
P36888

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C ATP 7 3
A C DFG 8 2
A C PDIG 9 2
A N ATP 0 18
A N ATP 2 15
A N MPP 3 13
A N MPP 4 9
A N MPP 5 6

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Legend

Color Name Hit Count