Pyridopyrimidinone Derivatives as Potent and Selective c-Jun N-Terminal Kinase (JNK) inhibitors

PDB Details

PDB ID
4Y46
Status
CURRENT
Deposition Date
2015-02-10
Modification Date
2015-05-06
Pubmed ID
25893042
Method
X-RAY DIFFRACTION
Resolution (Å)
2.04
UniProt Accessions
P53779

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 0 21
A C PDIG 1 19
A C DEF 3 14
A C DFG 4 8
A C EDI 5 5
A C PDIG 7 3
A N ATP 0 20
A N PIF 1 18
A N MT3 3 14
A N ATP 9 1

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Legend

Color Name Hit Count