Pyridopyrimidinone Derivatives as Potent and Selective c-Jun N-Terminal Kinase (JNK) inhibitors

PDB Details

PDB ID
4Y5H
Status
CURRENT
Deposition Date
2015-02-11
Modification Date
2015-05-06
Pubmed ID
25893042
Method
X-RAY DIFFRACTION
Resolution (Å)
2.06
UniProt Accessions
P53779

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 0 19
A C DEF 2 15
A C DFG 3 10
A C EDI 5 7
A C CMP 8 5
A N ATP 0 28
A N PIF 1 19
A N MT3 2 17

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Legend

Color Name Hit Count