Crystal structure of DYRK1A in complex with 10-Iodo-substituted 11H-indolo[3,2-c]quinoline-6-carboxylic acid inhibitor 5j

PDB Details

PDB ID
4YLJ
Status
CURRENT
Deposition Date
2015-03-05
Modification Date
2015-04-22
Pubmed ID
25730262
Method
X-RAY DIFFRACTION
Resolution (Å)
2.58
UniProt Accessions
Q13627

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 2 13
A C DRS 5 7
A C LBP 9 2
A C PDIG 10 2
A N PIF 0 22
A N ATP 1 18
A N ATP 3 13
A N MT3 6 5
A N ATP 7 4
A N DFG 8 4

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Legend

Color Name Hit Count