Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance.

PDB Details

PDB ID
5AP1
Status
CURRENT
Deposition Date
2015-09-14
Modification Date
2015-09-23
Pubmed ID
26202014
Method
X-RAY DIFFRACTION
Resolution (Å)
2.05
UniProt Accessions
P33981

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 0 18
A C CMP 1 18
A C ATP 5 5
A C AAS 6 5
A C AAS 7 5
A C ATP 8 4
A C EDI 9 2
A N MPP 1 17
A N ATP 3 15
A N MT3 4 15

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Legend

Color Name Hit Count