SYK catalytic domain complexed with a potent orally bioavailable thiazole inhibitor

PDB Details

PDB ID
5CXH
Status
CURRENT
Deposition Date
2015-07-29
Modification Date
2015-12-16
Pubmed ID
26320624
Method
X-RAY DIFFRACTION
Resolution (Å)
1.9
UniProt Accessions
P43405

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 3 11
A C LBP 7 4
A N DFG 3 8
A N ATP 4 6
A N MPP 6 5
A N DFG 7 2
A N MT3 10 2

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Legend

Color Name Hit Count