EGFR kinase (T790M/L858R) with inhibitor compound 27: ~{N}-(1~{H}-indazol-3-yl)-7,7-dimethyl-2-(2-methylpyrazol-3-yl)-5~{H}-furo[3,4-d]pyrimidin-4-amine

PDB Details

PDB ID
5EDR
Status
CURRENT
Deposition Date
2015-10-21
Modification Date
2016-01-20
Pubmed ID
26639762
Method
X-RAY DIFFRACTION
Resolution (Å)
2.6
UniProt Accessions
P00533

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 4 11
A C DRS 8 3
A N DFG 6 4
A N MPP 8 3

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Legend

Color Name Hit Count