Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle kinase 1 (MPS1) Using a Structure-Based Hydridization Approach

PDB Details

PDB ID
5EH0
Status
CURRENT
Deposition Date
2015-10-27
Modification Date
2016-05-11
Pubmed ID
27055065
Method
X-RAY DIFFRACTION
Resolution (Å)
2.18
UniProt Accessions
P33981

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 0 17
A C EDI 1 16
A C ATP 4 13
A C AAS 5 10
A C AAS 9 2
A N ATP 0 18
A N MPP 3 15
A N MT3 4 13
A N DFG 5 9

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Legend

Color Name Hit Count