Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle kinase 1 (MPS1) Using a Structure-Based Hydridization Approach

PDB Details

PDB ID
5EHY
Status
CURRENT
Deposition Date
2015-10-29
Modification Date
2016-05-11
Pubmed ID
27055065
Method
X-RAY DIFFRACTION
Resolution (Å)
2.26
UniProt Accessions
P33981

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 0 18
A C EDI 8 4
A N ATP 1 16
A N MPP 3 15
A N MT3 4 10
A N MT3 5 9
A N ATP 7 7

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Legend

Color Name Hit Count