Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle kinase 1 (MPS1) Using a Structure-Based Hydridization Approach

PDB Details

PDB ID
5EI2
Status
CURRENT
Deposition Date
2015-10-29
Modification Date
2016-05-11
Pubmed ID
27055065
Method
X-RAY DIFFRACTION
Resolution (Å)
2.67
UniProt Accessions
P33981

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 0 19
A C CMP 1 15
A C EDI 5 8
A C PDIG 8 2
A N ATP 0 17
A N ATP 4 13
A N MT3 6 4
A N DFG 7 3

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Legend

Color Name Hit Count