Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle kinase 1 (MPS1) Using a Structure-Based Hydridization Approach

PDB Details

PDB ID
5EI6
Status
CURRENT
Deposition Date
2015-10-29
Modification Date
2016-05-11
Pubmed ID
27055065
Method
X-RAY DIFFRACTION
Resolution (Å)
2.01
UniProt Accessions
P33981

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 0 17
A C ATP 5 11
A C CMP 6 6
A C AAS 8 2
A N ATP 1 16
A N MPP 2 16
A N MT3 3 14
A N DFG 6 8

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Legend

Color Name Hit Count