EGFR kinase domain mutant "TMLR" with pyridone compound 13: 4-[(2-methoxyphenyl)amino]-~{N}-[4-(4-methylpiperazin-1-yl)phenyl]-2-oxidanylidene-1~{H}-pyridine-3-carboxamide

PDB Details

PDB ID
5EM7
Status
CURRENT
Deposition Date
2015-11-05
Modification Date
2016-02-10
Pubmed ID
26819674
Method
X-RAY DIFFRACTION
Resolution (Å)
2.81
UniProt Accessions
P00533

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 3 14
A C DRS 8 2
A N ATP 5 7
A N MPP 6 5
A N MPP 7 5
A N DFG 8 4

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Legend

Color Name Hit Count