Structure of TYK2 with inhibitor 16: 3-azanyl-5-[(2~{S})-3-methylbutan-2-yl]-7-[1-methyl-5-(2-oxidanylpropan-2-yl)pyrazol-3-yl]-1~{H}-pyrazolo[4,3-c]pyridin-4-one

PDB Details

PDB ID
5F1Z
Status
CURRENT
Deposition Date
2015-12-01
Modification Date
2016-02-10
Pubmed ID
26701356
Method
X-RAY DIFFRACTION
Resolution (Å)
2.65
UniProt Accessions
P29597

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C AAS 4 10
A C PDIG 5 10
A N DFG 2 12
A N ATP 5 5
A N ATP 6 5
A N ATP 8 2
A N MPP 9 2

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Legend

Color Name Hit Count