EGFR (L858R, T790M, V948R) in complex with N-{3-[(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]phenyl}prop-2-enamide

PDB Details

PDB ID
5HG5
Status
CURRENT
Deposition Date
2016-01-08
Modification Date
2016-03-23
Pubmed ID
26756222
Method
X-RAY DIFFRACTION
Resolution (Å)
1.52
UniProt Accessions
P00533

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DFG 2 16
A C PDIG 10 2
A N MT3 1 16
A N PIF 3 13
A N MPP 4 9
A N ATP 5 6
A N MPP 6 4
A N MT3 7 3
A N MPP 10 1

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Legend

Color Name Hit Count