EGFR (L858R, T790M, V948R) in complex with 1-{(3R,4R)-3-[5-Chloro-2-(1-methyl-1H-pyrazol-4-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-yloxymethyl]-4-methoxy-pyrrolidin-1-yl}propenone (PF-06459988)

PDB Details

PDB ID
5HG7
Status
CURRENT
Deposition Date
2016-01-08
Modification Date
2016-03-23
Pubmed ID
26756222
Method
X-RAY DIFFRACTION
Resolution (Å)
1.85
UniProt Accessions
P00533

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DFG 1 17
A C EDI 5 10
A N MT3 0 18
A N PIF 1 16
A N ATP 4 12

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Legend

Color Name Hit Count