EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide

PDB Details

PDB ID
5HG8
Status
CURRENT
Deposition Date
2016-01-08
Modification Date
2016-03-23
Pubmed ID
26756222
Method
X-RAY DIFFRACTION
Resolution (Å)
1.42
UniProt Accessions
P00533

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DFG 1 14
A C DRS 7 4
A N MPP 0 17
A N MT3 1 15
A N ATP 2 12
A N PIF 5 8
A N MPP 9 3

Mapping Results Viewer

Use your mouse to drag, rotate, and zoom. Select structure to view on the right using dropdown.

Legend

Color Name Hit Count