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EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
PDB Details
PDB ID
5HG8
Status
CURRENT
Deposition Date
2016-01-08
Modification Date
2016-03-23
Pubmed ID
26756222
Method
X-RAY DIFFRACTION
Resolution (Å)
1.42
UniProt Accessions
P00533
Mapping Results
Chain
Terminus
Site
Consensus Site Rank
Consensus Site Population
A
C
DFG
1
14
A
C
DRS
7
4
A
N
MPP
0
17
A
N
MT3
1
15
A
N
ATP
2
12
A
N
PIF
5
8
A
N
MPP
9
3
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Chain: A
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Name
Hit Count
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Chain: A