EGFR (L858R, T790M, V948R) in complex with 1-[(3R,4R)-3-[({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-(trifluoromethyl)pyrrolidin-1-yl]prop-2-en-1-one

PDB Details

PDB ID
5HG9
Status
CURRENT
Deposition Date
2016-01-08
Modification Date
2016-03-23
Pubmed ID
26756222
Method
X-RAY DIFFRACTION
Resolution (Å)
2.15
UniProt Accessions
P00533

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DFG 4 10
A C PDIG 5 8
A C EDI 6 5
A C DRS 9 2
A N ATP 0 17
A N MPP 2 15
A N DFG 6 6
A N MPP 8 3

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Legend

Color Name Hit Count