The identification and pharmacological characterization of 6-(tert-butylsulfonyl)-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine (GSK583), a highly potent and selective inhibitor of RIP2 Kinase, GSK583 complex

PDB Details

PDB ID
5J7B
Status
CURRENT
Deposition Date
2016-04-06
Modification Date
2016-06-08
Pubmed ID
27109867
Method
X-RAY DIFFRACTION
Resolution (Å)
2.53
UniProt Accessions
O43353

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 3 9
A C CMP 4 8
A C DRS 6 8
A N ATP 0 18
A N MT3 3 14
A N MPP 4 12
A N ATP 5 10

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Legend

Color Name Hit Count